Arsenal vs Manchester United confirmed lineups: Holding in for Gabriel; Tuanzebe debuts

MANCHESTER, ENGLAND - NOVEMBER 19: Arsene Wenger, Manager of Arsenal (L) and Jose Mourinho, Manager of Manchester United (R) walk towards the tunnel after the final whistle during the Premier League match between Manchester United and Arsenal at Old Trafford on November 19, 2016 in Manchester, England. (Photo by Shaun Botterill/Getty Images)

Rob Holding is the only change made by Arsene Wenger, while Axel Tuanzebe makes his full debut for Manchester United as they face Arsenal at the Emirates

Holding starts in the back-three in place of Brazilian centre-back Gabriel, with Nacho Monreal and Laurent Koscielny his senior partners. Kieran Gibbs continues at left wing-back, while Mesut Ozil, Alexis Sanchez and Danny Welbeck are the attacking trio.

Meanwhile, Jose Mourinho has made eight changes to the side that faced Celta Vigo on Thursday as Axel Tuanzebe makes his full Manchester United debut at right-back.

David De Gea, Phil Jones, Chris Smalling, Michael Carrick, Juan Mata, Anthony Martial and captain Wayne Rooney are the other changes.

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